In this issue Joshi et al. found additional supporting evidence to indicate that soy can benefit men with prostate cancer. Vollbracht and colleagues found that intravenous vitamin C helped to reduce treatment-related side effects for women with breast cancer. Ruder and associates reported that adolescent and mid-life diet may play a role in the development of colorectal cancer. Tasevska and colleagues investigated the link between sugar and cancer development. Borch and associates found that low levels of physical activity are associated with an increased risk of mortality, and Pronk et al. found that increased physical activity is associated with lower breast cancer risk. Kastelein and associates reported that use of statins and nonsteroidal anti-inflammatory medicines helped to slow the progression of Barrett’s esophagus. Naing and colleagues reported that utilization of complementary and alternative medicine is common in patients in phase 1 clinical trials. Lim and associates found that patients with incurable cancer benefited from acupuncture and nurse-led care also was beneficial in the longer term. Pardanani and colleagues found that low levels of vitamin D are common in cancer patients and that its relevance to prognosis is limited. In our study of the month, Parkin et al. drew a link between lifestyle and environmental risk factors for cancer such as smoking, alcohol consumption, diet, exercise, etc. and provided a fractional analysis of the incidence of 18 different types of cancer in the UK in 2010.